Therapeutic hypothermia: Not so hot for cerebral protection after cardiac arrest or traumatic brain injury
The role of therapeutic hypothermia in the management of traumatic brain injury and cardiac arrest has been called into question. Mehnaz Khan and Simon Stacey review the evidence of recent trials to determine what can be perceived as best practice.
Therapeutic hypothermia (TH) has played a major role in the management of out-of-hospital cardiac arrest (OOHCA) and often in-hospital cardiac arrest following seminal publications in the New England Journal of Medicine which led to its incorporation into the ESC guidelines in 2002 [1,2]. Similarly, TH has been a part of the recommendations issued by the Brain Trauma Foundation (BTF) for the management of traumatic brain injury (TBI) since 2007 [3]; however, since then, a systematic review published in…
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